Lazaretto is a term synonymous with quarantine, particularly for maritime travelers. In the days of the slave trade, incoming slave ships would access a quarantine station on Tybee Island via Lazaretto Creek, hence the name. 

The Lazaretto Creek Boat Ramp is located on the North side of US-80, east of the Fort Pulaski Park entrance. It is comanaged under a joint agreement between the National Park Service, Chatham County Parks and Recreation, and the Georgia Department of Natural Resources.  

The facility includes a 3-lane boat ramp, a floating dock for loading and unloading, parking for vehicles and trailers, restroom facilities, and a large fishing pier. The facility is open 24 hours a day, 7 days a week, and is free of charge.