Crowe's Purchase is a historic district in Yarmouth, Massachusetts, that encompasses a 17th-century land grant and the surviving buildings associated with it. The district covers about 300 acres of land along the north shore of Bass River, extending from Willow Street in the west to Summer Street in the east. The land was granted to John Crowe in 1643 by the Plymouth Colony and remained in his family until the late 18th century. The district includes several historic buildings, such as the Crowe Homestead, a saltbox house built around 1690; the Crowe Barn, a large English barn dating to the early 18th century; and the Crowe Cemetery, where several generations of the Crowe family are buried. The district was listed on the National Register of Historic Places in 1999.

Crowe's Purchase is located off of MA-28.