The Derby Line Welcome Center serves as a gateway to the North East Kingdom for Canadian traffic entering the United States. The Welcome Center is staffed with courteous, knowledgeable travel professionals who assist with directions, where to stay and dine, and current happenings.

Travelers find information on maple sugarhouses, cheesemakers, breweries, wineries, farmers' markets, skiing, golfing, camping, hiking, fishing, hunting, boating, bicycling, music, theater, museums, galleries, antiquing, lodging, dining, bookstores and shopping.

This section of Interstate 91 opened in 1962. The facility was constructed in 1968.