The 1,799-acre Indian Creek Wildlife Area is one mile east of Fayetteville in northern Brown County. County and township roads provide good access to the area from US-50 and US-68.

The terrain is very flat, except for the narrow valleys of Indian Creek and Little Indian Creek, which flow westerly through the area. Approximately 60 percent of the area is open land, consisting of crop fields intermixed with fields of broomsedge and scattered sassafras, soft maple, pin oak, and gum. The remainder is divided equally between woods and brush. Pin oak, hickory, soft maple, and beech are the principal tree species. Cottonwood and sycamore are common along the streams.