Marana, Arizona 85653Santa Cruz River Official Website
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The Santa Cruz River is about 184 miles long. It begins in the high grasslands of the San Rafael Valley east of Patagonia. At first, it runs south into Sonora Mexico for several miles before it changes its mind and heads north back into Arizona where it passes the early Spanish missions of Tumacacori and San Xavier del Bac, and the old Spanish Presidio de Tucson about 70 miles north of the International Border.